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Entamoeba histolytica is a microscopic intestinal parasite that can be detected in stool. It is not considered a normal part of the dog’s gut microbiome. Detection may reflect exposure through water, food, or surroundings that have been contaminated with faeces. Entamoeba histolytica mainly affects the large intestine, where it can irritate the intestinal lining and, in more significant cases, cause tissue damage. When Entamoeba histolytica affects the gut, it is mainly associated with persistent diarrhoea, loose stools, mucus in stool, blood in stool, abdominal discomfort, reduced appetite, weight loss, or poor general condition. If Entamoeba histolytica is detected, especially together with ongoing diarrhoea, blood or mucus in stool, weight loss, or lethargy, veterinary follow up is recommended to assess the finding and decide whether treatment, hydration support, and hygiene measures are needed.

